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Michael, A.
- Studies on Antivenom Activity of Andrographis paniculata and Aristolochia indica Plant Extracts against Daboia russelli Venom by in Vivo and in Vitro Methods
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Authors
Affiliations
1 Dept. of Microbiol., Nehru Arts & Science College, IN
2 PSG College of Arts and Science, Coimbatore, IN
1 Dept. of Microbiol., Nehru Arts & Science College, IN
2 PSG College of Arts and Science, Coimbatore, IN
Source
Indian Journal of Science and Technology, Vol 2, No 4 (2009), Pagination: 76-79Abstract
Methanolic extracts of Andrographis paniculata and Aristolochia indica plants were tested for antivenom activity against Daboia russelli venom. Both plant extracts effectively neutralized the D. russelli venom induced lethal activity. About 0.15 mg of A. paniculata and 0.14 mg of A. indica plant extracts were able to completely neutralize the lethal activity of 2LD50 of D. russelli venom. Various pharmacological activities including edema, haemorrhagic, coagulant, fibrinolytic and phospholipase activities were studied and these pharmacological activities were significantly neutralized by both the plant extracts. The above observations confirmed that A. paniculata and A. indica plant extracts possess potent snake venom neutralizing capacity and could potentially be used for therapeutic purposes in case of snakebite envenomation.Keywords
Antivenom, Plant Extracts, Snake BiteFull Text
References
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- Chicken Egg Yolk Antibodies (IgY) as an Alternative to Mammalian Antibodies
Abstract Views :812 |
PDF Views:218
Authors
A. Michael
1,
S. Meenatchisundaram
2,
G. Parameswari
3,
T. Subbraj
3,
R. Selvakumaran
4,
S. Ramalingam
5
Affiliations
1 Dept. of Microbiology, PSG College of Arts and Science, Coimbatore- 641014
2 2Dept. of Microbiology, Nehru Arts and Science College, Coimbatore - 641105, IN
3 Dept. of Microbiology, PSG College of Arts and Science, Coimbatore- 641014, IN
4 Sankara College of Science and Commerce, Coimbatore – 641035., IN
5 PSG Institute of Medical Science and Research, Coimbatore - 641004, IN
1 Dept. of Microbiology, PSG College of Arts and Science, Coimbatore- 641014
2 2Dept. of Microbiology, Nehru Arts and Science College, Coimbatore - 641105, IN
3 Dept. of Microbiology, PSG College of Arts and Science, Coimbatore- 641014, IN
4 Sankara College of Science and Commerce, Coimbatore – 641035., IN
5 PSG Institute of Medical Science and Research, Coimbatore - 641004, IN
Source
Indian Journal of Science and Technology, Vol 3, No 4 (2010), Pagination: 468-474Abstract
Chicken eggs present an ideal alternative antibody source to mammals, as the IgY in the chicken's blood is transported to the egg and accumulates in the egg yolk in large quantities. The existence of an IgG like molecule in avian eggs, referred to as IgY, has been well documented in recent studies and extensive research has been carried out on its characterization, production and purification. The yolks of eggs laid by immunized chicken have been recognized as an excellent source of polyclonal antibodies for over a decade. This simple non invasive approach presents an appealing alternative to conventional polyclonal antibody production methods. The use of immunoglobulin therapy broadens the arsenal available to combat pathogens in medicine and IgY is a promising candidate, both as an alternative to antibiotics and as a useful tool in research and diagnostics.Keywords
Chicken Antibody Igy, Antivenom, Passive Immunotherapy, SalmonellaFull Text
References
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- Snake Bite and Therapeutic Measures: Indian Scenario
Abstract Views :348 |
PDF Views:188
Authors
Affiliations
1 Dept. of Microbiol., Nehru Arts & Science College, IN
2 Dept. of Microbiol., PSG College of Arts & Science, Coimbatore, IN
1 Dept. of Microbiol., Nehru Arts & Science College, IN
2 Dept. of Microbiol., PSG College of Arts & Science, Coimbatore, IN
Source
Indian Journal of Science and Technology, Vol 2, No 10 (2009), Pagination: 69-73Abstract
The Indian subcontinent, being tropical, harbors a variety of snakes. Every year ~15,000 people reportedly die due to snakebites in India. Until now, horse polyvalent antivenom is the only specific treatment for snake venom poisoning. This paper describes the occurrence of snake bite in India and their therapeutic measures in the case of snake bite envenomation.Full Text
References
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